Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology
نویسندگان
چکیده
منابع مشابه
Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology
MOTIVATION The accuracy of reference genomes is important for downstream analysis but a low error rate requires expensive manual interrogation of the sequence. Here, we describe a novel algorithm (Iterative Correction of Reference Nucleotides) that iteratively aligns deep coverage of short sequencing reads to correct errors in reference genome sequences and evaluate their accuracy. RESULTS Us...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2010
ISSN: 1460-2059,1367-4803
DOI: 10.1093/bioinformatics/btq269